The Cellular Architecture

by | 2026-Jul-Tue | article

The biology of knowledge was the metaphor. This is the executable architecture. In The Biology of Knowledge article, I used a metaphor comparing how living cell manages it knowledge to characterize four digital assets: data as genome, information as transcriptome,...

The Biology of Knowledge

by | 2026-Jul-Fri | article

“One cannot beat four billion years of evolution managing knowledge” We keep treating enterprise data like inventory in a warehouse: catalogue it, lock it, audit it, and hope it stays where we put it. Then we bolt an AI on top and act surprised when it...

The Definition of Success

by | 2026-Jun-Fri | article

Your Team Agreed on Success? You Have a Problem Knowledge Management start with knowing what you want. This article explains how semantics and AI can help you better define what you want and align it with what other want. When everyone nods at the word...

HTA precedent is everywhere. Almost none of it is queryable.

by | 2026-May-Fri | article

Every Health Technology Assessment produced in Europe (by UK NICE, National Institute for Health and Care Excellence, G-BA (Germany, Gemeinsamer Bundesausschuss), HAS (France, Haute Autorité de Santé), AIFA (Italy, Agenzia Italiana del Farmaco), AEMPS (Spain, Agencia...

The Great AI Divide

by | 2026-May-Mon | article

The Illusion of Progress AI is everywhere. In presentations, strategy decks, performance reviews. It writes faster than we do, answers questions instantly, and seems to make organizations more efficient overnight. The promise is seductive: more output, less effort,...

IDMP: We built a map. Pharma needs an instrument.

by | 2026-Apr-Mon | article

Two years ago, the IDMP ontology (IDMP-O) won the BioITWorld award [https://pistoiaalliance.org/news/pistoia-alliance-wins-2024-bio-it-world-innovative-practices-award-for-idmp-pre-competitive-collaboration/]. We built the first version at Novartis, released it into...